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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJA1
All Species:
26.06
Human Site:
S279
Identified Species:
63.7
UniProt:
P17302
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17302
NP_000156.1
382
43008
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Chimpanzee
Pan troglodytes
XP_001164302
382
43020
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Rhesus Macaque
Macaca mulatta
XP_001109566
382
43034
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Dog
Lupus familis
XP_539602
333
37317
S237
H
L
L
C
R
C
L
S
R
G
M
K
A
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
P23242
382
42986
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Rat
Rattus norvegicus
P08050
382
43013
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508248
340
38783
I244
K
D
R
V
K
G
R
I
D
P
Y
L
A
A
T
Chicken
Gallus gallus
P14154
381
43107
P279
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
K
Frog
Xenopus laevis
P16863
379
42943
S279
S
S
P
T
A
P
M
S
P
P
G
Y
K
L
V
Zebra Danio
Brachydanio rerio
O57474
381
43436
S279
S
S
P
T
A
P
L
S
P
M
S
P
P
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
44.7
N.A.
97.3
97.6
N.A.
70.1
93.4
86.1
80.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.7
60.4
N.A.
99.4
99.4
N.A.
75.9
97.3
93.4
89
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
0
13.3
53.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
0
13.3
60
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
70
0
0
0
0
0
0
0
20
10
0
% A
% Cys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
10
10
0
10
60
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
10
10
0
10
% K
% Leu:
0
10
10
0
0
10
70
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
10
0
10
60
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
70
0
10
70
0
10
70
20
10
70
60
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
10
0
10
0
10
0
0
0
0
0
10
% R
% Ser:
80
70
0
0
0
0
10
80
0
10
60
0
0
0
0
% S
% Thr:
0
0
10
70
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _